Omicron variant replicates better in children’s noses, says study
Researchers at the University of Queensland in Australia found that the Omicron variant of the coronavirus replicates better in children’s nose cells than previous strains.
The discovery, published this week in the scientific journal PLOS Biologyhelps explain why the number of pediatric infections was higher during the current wave of the pandemic compared to previous ones.
Scientists evaluated the behavior of three virus variants – the original, Delta and Omicron – in contact with primary nasal epithelial cells (NECs) from 23 children and 15 healthy adults in laboratory tests.
Anvisa approved, on December 16, the application of Pfizer’s immunizing agent in children aged 5 to 11 years. For this, a pediatric version of the vaccine will be used, called Comirnatybaona/Getty Images
The vaccine is specific for children and has a different concentration than that used in adults. The dose of Comirnaty is equivalent to a third of that applied to people over 12 years oldIgo Estrela / Metropolis
The lid of the vaccine vial will be orange, to facilitate identification by the immunization teams and also by fathers, mothers and caregivers who will take the children to receive the drug application.Aline Massuca/Metropolis
***child-vaccination-what-you-knowprofessionals pushing patient in gurney
Since the beginning of the pandemic, more than 300 children between the ages of 5 and 11 have died from the coronavirus in Brazil.ER Productions Limited/Getty Images
This corresponds to 14.3 deaths per month, or one every other day. In addition, according to data from the Ministry of Health, the prevalence of the disease in children is significant. Apart from the number of deaths, there are thousands of hospitalizationsGetty Images
According to Fiocruz, vaccinating children against Covid is necessary to prevent the circulation of the virus at high levels, in addition to ensuring the health of the little ones.Vinícius Schmidt/Metropolis
To discuss childhood immunization, the Ministry of Health opened a public consultation and announced that pediatric vaccination would start on January 14. In addition, the presentation of a medical prescription will not be mandatory.Igo Estrela / Metropolis
According to the folder, the immunizing agent used will be that of pharmaceutical Pfizer and the suggested interval between each dose will be eight weeks. If the minor is not accompanied by his parents, he must present a written term signed by the guardian Hugo Barreto / Metropolis
The decision of the Ministry of Health to extend the range of doses of the immunizer contradicts Anvisa’s guidance, which advocates a three-week break between one application and another for children aged 5 to 11 years.Rafaela Felicciano / Metropolis
In addition, although a medical prescription is not required for vaccination, the federal government recommends that parents consult a health professional before taking their children to be vaccinated.Aline Massuca / Metropolis
According to Pfizer data, about 7% of children who received a dose of the vaccine had some reaction, but in only 3.5% the events were related to the immunizing agent. none of them were seriousIgo Estrela / Metropolis
Countries such as Israel, Chile, Canada, Colombia, United Kingdom, Argentina and Cuba, and the European Union itself, for example, are some of the places that have authorized vaccination against Covid-19 in children.Getty Images
In the United States, childhood immunization began on November 3. To date, more than 5 million children have received the Covid-19 vaccine. No deaths were recorded and serious adverse events were rare. baona/Getty Images
vaccinated childGetty Images
A study released by Butantan in January shows that there were no reports of serious adverse effects among the 4,000 children between 6 and 35 months of age who participated in the survey.Getty Images
The Butantan Institute, responsible for the manufacture of the Coronavac vaccine in the national territory, should send Anvisa more data on the age group from 3 to 5 years old to increase the number of people to be immunized by the formula Getty Images
While vaccines are not approved for younger children, scientific research has already shown that vaccinated breastfeeding mothers pass antibodies to their children via breast milk. Getty Images
They found that the original virus replicates at significantly lower levels in the cells lining children’s noses compared to those of adults. However, this behavior changed with Ômicron.
The antiviral defenses present in children’s noses are less pronounced for Omicron, according to the researchers. The variant also reproduced more easily in these cells compared to Delta and the original version of the virus, increasing the risk of infection.