Berlin.
Stress causes us to age biologically. US researchers have once again been able to prove this. However, one realization surprised her.
Stressful stimuli cause people to age biologically. One published in the journal Cell Metabolism Study provides further evidence of this. The good news according to the study: those who reduce stress and strain can do so aging apparently turning back.
A person’s biological age can differ from their chronological age. It is not measured in years of life or dates, but in the condition of the genome. A higher biological age, influenced for example by poor diet or lifestyle, can do this Risk increase for illness or death.
Researchers led by aging researcher Vadim Gladyshev from Harvard Medical School and cell biologist James White from Duke University School of Medicine (both USA) initially investigated the influence of stress on biological age using mice. In the first phase of their research, they connected for it surgical three-month-old mice with 20-month-old mice, allowing blood to flow between the two rodents.
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Biological age: “Something many didn’t think was possible”
Over the course of three months, the study authors said, the biological age of the younger mice increased as they shared blood with their older counterparts. However, after the young mice were separated and separated for two months recover could, the change in their biological age reversed again. “It’s something a lot of people didn’t think was possible,” James White told The Scientist magazine.
Prompted by the results in mice, Gladyshev, White and their colleagues decided to investigate the same question in humans. They analyzed the DNA age of blood samples of people who were temporarily exposed to stressful situations – they collected the data themselves or obtained it from publicly available databases.
Patients exposed to emergency surgery, pregnancy, or severe COVID-19 reportedly showed broadly the same trend as mice: an increase in biological age followed by a return to disease initial valuesas soon as the stressful stimulus ended.
Are there future tests that can measure recovery?
“There are very, very few studies that have looked at biological age before and after medical intervention,” Daniel Belsky, an epidemiologist at Columbia University who was not involved in the study, told The Scientist. The collection of Data before and after a large number of interventions is a really important step. Belsky reviewed the study and is collaborating with some of the authors on unrelated research, according to the publication.
A possible clinical utilization of the study results is still a long way off, Belsky continued. And yet the observations could point to a Future indicate that tests would be developed to measure how patients recovered from medically-related stress. Belsky: “It could be that one day we’ll be able to use these tests to learn things about patients that we can’t see today.” (kai)
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