researchers from University of Glasgow, in the United Kingdom, claim to have found the key to developing a new treatment against pancreatic cancer. They identified immune cells that help tumors grow in the gland and could be used as a target for a new immunotherapy.
Coffelt’s team studied how the immune system works as cancer spreads in the pancreas. Thus, they developed new strategies to attack the tumor. The results were disclosed in an article published on the university’s website this Friday (3/31).
The researchers noted that gamma delta T immune cells play an important role in tumor advancement by controlling the activity of other types of immune cells. This creates an ideal environment for the tumor to grow and spread to other parts of the body.
“So understanding why and how pancreatic cancer is able to hide from the immune system and spread could allow us to find new ways to reduce, or even prevent, this from happening.” , Chris Macdonald, in a statement.
According to the National Cancer Institute (Inca), cancer is one of the main public health problems in the world and is one of the four main causes of death before the age of 70 in several countries. As it is an increasingly common problem, the sooner it is identified, the greater the chances of recovery.boonchai wedmakhand
****Photo-lady-sitting-with-hands-on-belly.jpgTherefore, it is important to be aware of the signs that the body gives. Although some tumors have no symptoms, cancer often causes changes in the body. Know some signs that may appear in the presence of the diseasePhynart Studio/ Getty Images
****Photo-woman-on-a-scale.jpgWeight loss for no apparent reason can be one of the main symptoms of different types of cancer, such as: stomach, lung, pancreas, etc.Flashpop/ Getty Images
****Photo-person-with-hand-on-bosom-2.jpgPersistent changes in skin texture for no apparent reason can also be a red flag, especially if they are bumps and lumps in the breast, neck, groin, testicles, armpit and stomach.FG Trade/ Getty Images
****Photo-man-with-cough.jpgPersistent cough, despite being a common symptom of several diseases, should be investigated if it continues for more than four weeks. If it is accompanied by shortness of breath and blood, for example, it may be an indication of lung cancer.South_agency/ Getty Images
****Photo-paint-being-investigated.jpgAnother characteristic sign of the existence of cancer is the change in the appearance of moles. Changes in size, color, and shape should also be investigated, especially if they flake, bleed, or show retained fluid.Peter Dazeley/Getty Images
****Photo-person-in-pain.jpgThe presence of blood in the stool or urine can be a sign of cancer of the kidneys, bladder or bowel. In addition, pain and difficulties when urinating should also be investigated.RealPeopleGroup/ Getty Images
****Photo-person-with-hand-on-bosom.jpgPain for no apparent reason and lasting more than four weeks, frequently or intermittently, may be a sign of cancer. This is because some tumors can press on bones, nerves and other organs, causing discomfort. ljubaphoto/ Getty Images
*****Photo-man-with-the-belly.jpgStrong, recurrent heartburn, which is painful and apparently does not go away, can indicate various types of diseases, such as throat or stomach cancer. In addition, difficulty and pain when swallowing should also be investigated, as they may be a sign of esophageal cancer.DjelicS/ Getty Images
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pancreas cancer
Pancreatic cancer has a high mortality rate: the malignant tumor usually does not cause symptoms in the early stages, leading to late diagnosis, when it has already spread to other parts of the body.
In Brazil, it is responsible for about 1% of all types of cancer diagnosed and for 5% of all deaths caused by the disease, according to data from the National Cancer Institute (Inca).
Surgery to remove the tumor is currently the only treatment indicated with the greatest chance of cure, since immunotherapy, used for various types of cancer, generally does not work for these patients.
“Pancreatic cancer is a highly metastatic disease, often spreading throughout the body even before the first symptoms appear. Curative surgery is only possible if the disease is still contained in the organ. Even for patients who cannot have surgery, chemotherapy is much more effective if the cancer has not spread,” says Macdonald.
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