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Biological aging is a process that causes a gradual decline in physiological functions. It includes increased damage and loss of function in various organs and systems.
According to a new study, recently published in Cell Metabolism, biological age in rats and humans increases rapidly when exposed to stress. Research also reveals the possibility of reversing this process, which could have significant implications for future treatments.
Biological age refers to a person’s age, as determined by their physical and physiological state, including factors such as changes in gene expression patterns and the accumulation of cell and tissue damage. Biological age is affected by many factors, including diseases, lifestyle and environment.
Chronological age, on the other hand, is simply an individual’s age as measured by the passage of time since birth. There is no connection between biological and chronological age. A person’s biological age can be more or less than their chronological age, reported the Interesting Engineering.
Very little is known about the malleability and reversibility of biological age. A team led by James White of Duke University School of Medicine and Vadim Gladyshev of Brigham and Women’s Hospital at Harvard Medical School set out to explore the extent of the reversibility of biological age.
The team used DNA methylation clocks, which are epigenetic biomarkers that measure changes in the methylation patterns in our DNA that occur throughout our lifetime. chronological aging. The humans and mice were then subjected to a variety of stress stimuli.
The researchers found that biological age increased during brief periods of stress. However, they noted that this change was temporary and reverted after recovery. The researchers also observed a transient change in biological age during pregnancy, COVID-19 infection and after surgery, both in mice and humans, which also reversed after recovery.
A biological age reversibility it’s an exciting discovery that opens the door to new therapies. The authors suggest that this observation can be used to predict anti-aging interventions.
Stress is a prevalent issue in our society, whether related to work, school or social life. As a result, recovery from stress plays a significant role in prolonging life.
ZAP // 
