Scientists at the Institute of Metabolic Science at the University of Cambridge, UK, have developed a fully automated device capable of controlling glucose levels in adults with type 2 diabetes.

Initial tests showed that the “artificial pancreas” significantly reduced the time that patients remained with high levels of sugar and doubled the intervals in which they had adequate levels of glucose, compared to the traditional treatment.

The results of the study were published on Wednesday (11/1) in the journal Nature Medicineand suggest that the device offers a safe and effective way to improve disease management.

“Many people with type 2 diabetes struggle to control their blood sugar levels using currently available treatments such as insulin injections. Artificial pancreas can provide a safe and effective approach to help them. The technology is simple to use and can be safely implemented at home,” says study author Charlotte Boughton.

The new insulin delivery system, called CamAPS HX, continuously responds to the patient’s blood glucose levels by sending information to an application installed on the user’s cell phone. It has a glucose monitor, insulin pump and an algorithm that predicts the amount of hormone needed to keep glucose levels within the target range, customizing treatment.

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Study

The research had the participation of 26 adults diagnosed with the disease. They were divided into two groups. The first received conventional diabetes treatment, with daily insulin injections, for eight weeks, and then spent another eight weeks using the new device. The second team did the opposite.

The researchers evaluated the proportion of time that patients spent with glucose levels between 3.9 and 10.0 mmol/L, considered the adequate range. On average, adults using the artificial pancreas spent two-thirds (66%) of the study period on controlled glucose, twice the time achieved with standard therapy (32%).

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While on CamAPS HX, participants spent only 33% of their time with glucose levels above 10.0 mmol/L, which is considered high. On the other hand, those using daily insulin injections remained 67% of the time with glucose levels above 10.0 mmol/L.

Overall, mean glucose levels decreased from 12.6 mmol/L during standard therapy with insulin injections to 9.2 mmol/L when using the device. Glycated hemoglobin (HbA1c) was reduced from 8.7% to 7.3%.

Type 2 diabetes

Type 2 diabetes is a chronic disease, characterized by the body’s resistance to insulin or production below ideal levels of the hormone, causing increased blood sugar levels.

Symptoms include dry mouth, increased urge to urinate, thirst, and unexplained weight loss. It can lead to complications like blindness and diabetic ulcers.

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The post Type 2 diabetes is controlled with “artificial pancreas”, shows study first appeared on Metropolis.

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