People infected with the coronavirus have an 88% lower risk of being hospitalized or dying from Covid-19 if they get sick again in the next ten months, compared with those who were not previously infected, according to a study published this Thursday ( 2/16) in the scientific journal The Lancet.
Research by scientists at the University of Washington School of Medicine in the United States is considered the most comprehensive to provide evidence on the protection generated by natural immunity by different variants of the coronavirus and how it decays over time.
The survey was based on the review and meta-analysis of 65 studies, carried out in 19 countries, which compared the reduction in the risk of Covid-19 among unvaccinated people who were infected by Sars-CoV-2 to unvaccinated individuals, without infection. previous year, until September 2022.
Protection against re-infection by one of the coronavirus variants in the pre-Omicron period was approximately 85% at one month and dropped to 79% at ten months.
However, the identification of Omicron and its variants changed this scenario significantly, increasing the recurrence of reinfections worldwide.
According to the North American review, people who had been infected by one of the previous strains (Alpha, Delta, etc.) and had contact with the first subvariant of Omicron (BA.1), showed strong protection against new infections in the first month (79 %), but it fell quickly, reaching only 36% in about ten months – a much lower percentage than previously observed.
Six of the analyzed studies showed significantly reduced protection against the BA.2 and BA.4/BA.5 sublines when the previous infection was with one of the first strains. The level of defenses was higher when the patient had already been contaminated by Omicron.
Patients who were previously infected with the original strain of the virus or the Alpha, Delta and BA.1 variants had a defense against reinfection, symptomatic illness and severe illness similar to that obtained after two doses of mRNA vaccines, such as those from Pfizer / BioNTech and from Moderna.
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Faced with the pandemic scenario and the expansion of the booster dose, some people are still wondering about the importance of the third dose of the vaccine against Covid-19stock
*** Vaccination of children against Covid-19
The booster dose must be administered at least four months after the individual completes the initial vaccination schedule. The extra application serves to increase the amount of memory cells and further strengthen the antibodies they produce.Rafaela Felicciano/Metropolises
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***Influenza flu vaccination
Experts point out that one of the main measures provided by the booster dose is the expansion of the immune response. The third dose causes an increase in the amount of antibodies circulating in the body, which reduces the chance of the immunized person getting sick.Tomaz Silva/Agência Brasil
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For the elderly and immunosuppressed, the booster dose increases the effectiveness of immunization, since these groups do not develop an adequate immune responseHugo Barreto/Metropolises
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***adult vaccine
Another important measure is to reduce the chance of infection in case of new variants. The antibody promoted by the vaccine is directed to the strain that gave rise to the formula and, in this process, people also produce antibodies that have diversity. The greater the reach of the proteins that defend the organism, the greater the probability that some will bind to the new variantWestend61/GettyImages
*** Vaccine against covid _ Coronavac _ butantan
The director of the Brazilian Society of Immunizations (SBIM) and member of the Technical Advisory Committee of the National Immunization Program of the Ministry of Health, Renato Kfouri says that the mixture of vaccines from different laboratories is a Rafaela Felicciano/Metropolises
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***covid vaccine Increase in the number of covid-19 and Influenza cases in Brazil 6
A study conducted by the University Hospital Southampton NHS Foundation Trust in the United Kingdom showed that people who received two doses of AstraZeneca had a 30-fold increase in antibody levels after a Moderna booster, and a 25-fold increase with a booster. pfizerArthur Menescal/Metrópoles Special
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Reactions to the booster dose are similar to the previous two doses. Mild to moderate symptoms such as excessive tiredness and pain at the injection site are expected. However, there are also reports of symptoms that include local redness or swelling, headache, muscle pain, chills, fever or nausea.Rafaela Felicciano/Metropolises
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***With low demand, vaccination against H1N1 in Goiânia focuses on i
It is worth noting that the use of three doses has the main objective of reducing the number of severe cases and the number of hospitalizations due to Covid-19.Vinícius Schmidt/Metrópoles
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focus on vaccination
Although the infection plays an important role in the body’s natural protection against new contacts with the virus, researchers point out that vaccination is still the safest way to acquire immunity.
“Vaccines remain important for everyone, protecting high-risk populations such as those over 60 years of age and those with comorbidities. This also includes populations that have not been previously infected,” says co-author of the article, Caroline Stein.
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